Naproxen is a common NSAID used for pain relief and fever reducer. It has the chemical formula C14H14O3. It works through inhibiting the body’s production of prostaglandins, therefore preventing pain and inflammation. It is available over-the-counter at lower dosages, and through prescription at higher dosages. As a NSAID, it carries a risk of heart attack, stroke, and gastrointestinal bleeding. Naproxen can be retained and analyzed using the Primesep 100 stationary phase column. The analysis utilizes an isocratic method with a simple mobile phase consisting of water and acetonitrile (MeCN) with phosphoric acid as a buffer. Detection is performed using UV.
The HPLC Method for Analysis of Naproxen on Alltesta™ Gradient is designed for Naproxen, a drug compound. Naproxen is a common NSAID used for pain relief and fever reducer.
Run the separation on Primesep 100 (4.6 x 150 mm, 5 um, 100 A, dual ended), SKU 100-46.150.0510. Typical mobile phase: MeCN, 55% 55% H2SO4, 0.2%; H2O 45%.
Operate on Alltesta™ Gradient with 275 nm. Flow rate: 1. Injection volume: 1. Run time: 5.
Our application team can help you adapt this method or develop a new one for your specific needs.
Last updated: Dec 3, 2025
